Coffee (caffeine) and its Effects in the Human Body
Effects of Caffeine
What caffeine does to the body
There is no requirement of caffeine in the human diet for the body to function properly.
Caffeine is a stimulant of the central nervous system (CNS), the cardiac muscle (increases heart rate), and respiratory system (relaxes air passages permitting improved breathing, and allows some muscles to contract more easily).
It acts as a diuretic (increases the rate of bodily urine excretion) and delays fatigue (having the effect of warding off drowsiness and restoring alertness). For these reasons, caffeine is the most popular drug in use throughout the world.
The effects you might notice after consuming a large cup of coffee, tea, or energy drink are:
- Cold hands
- Muscles tensing up
- Feelings of excitement
- Increased heart beat
- Alertness
- Sinuses clearing
These effects are heightened if the person doesn’t normally consume caffeine or if a person has been on a break from having caffeine daily.
Do Theophylline and Theobromine have the same effects?
The related alkaloids theophylline (found mainly in tea) and theobromine (in cocoa beans, cola nuts and tea) act as a cardiac stimulant, smooth muscle relaxant, diuretic, and vasodilator (widening or dilating blood vessels in the body).
Some people find them to have a better stimulating effect than caffeine, while others find them not as effective. When determining the caffeine content of a food or beverage, these two related alkaloids aren’t included in the total amount.
How caffeine interacts with the body
Generally it is absorbed by the body very quickly – caffeine enters the bloodstream through the mouth, esophagus, stomach, and small intestine with its effects felt as soon as 15 minutes after consumption. It is completely absorbed within 45 minutes of ingestion. Caffeine does not accumulate in the bloodstream nor is it stored in the body, but it does persist – only about ½ is eliminated in the urine within 4-6 hours.
Caffeine does not suppress the appetite, although it does increase the level of circulating fatty acids, thereby enhancing fat oxidation. This is why caffeine is used by runners and endurance trainers, although it is most effective in non-habitual users. Also, contrary to popular belief, the effects of alcohol are not reduced by caffeine, although as mentioned above it can provide temporary relief from fatigue and drowsiness and from migraine headaches.
Caffeine sensitivity refers to the amount of caffeine that will produce negative side effects in a particular person. Regular caffeine consumption reduces sensitivity to caffeine, and a higher intake is needed for the same effects. So caffeine is considered to be an addictive drug. Some can consume large amounts of caffeine without any problems, while others have side effects from even the smallest amounts.
When caffeine intake is reduced, the body then becomes oversensitive to a chemical in the brain (adenosine) relevant to the sleep process, causing blood pressure to drop dramatically, producing an excess of blood in the head area (not necessarily on the brain) and leading to a headache often lasting several days. Other withdrawal symptoms reported are fatigue and muscle pain, irritability, inability to work, nervousness, restlessness, and feeling sleepy, and in extreme cases, nausea and vomiting. Gradual reduction of caffeine intake abates these symptoms.

Levels of Caffeine Intake
| Intake Level | Amount | Effects |
|---|---|---|
Moderate | 250mg or Three 8oz/230ml cups of coffee | Has no apparent health risk in most individuals. |
Excessive | 500mg+ or Six 8oz/230ml cups of coffee | Can increase alertness, but also reduce fine motor coordination and cause insomnia, headaches, dizziness and nervousness. |
Dangerous | 1000mg+ or 12 or more cups of coffee | Can cause jitters, rapid heartbeat, nausea, anxiety attacks, heart palpitations, insomnia, sweating, dizziness, vomiting, cardiac arrest. |
Lethal | 10g or 170mg/kg of body weight or 80 cups of coffee. | This assumes the caffeine was consumed rapidly. Cardiac arrest. See also Death by Caffeine. |
Sources of Caffeine

The Caffeine Molecule
Caffeine is an alkaloid compound, which in pure form is odorless and bitter in taste.
Caffeine is one of many alkaloids (including theophylline and theobromine) which occur naturally and in varying amounts in leaves, seeds, and fruits of more than 60 plants.
These plant caffeine sources include:
- Coffee (from which the beans are used)
- Tea (leaves)
- Cacao (pods)
- Cola or kola (nuts)
- Yerba matè (leaves)
- Guarana (berries)
- Yaupon holly (leaves)
Caffeine is consumed from these sources in beverages and foods such as tea, coffee, chocolate, cocoa, matè, caffeinated soft drinks, caffeinated pills, coffee beans, and some drugs (pain killers such as Excederine).
Coffee comes second only to petroleum as the world’s most widely traded commodity.
Coffee Preparation Methods
The coffee beverage may be produced by one of a number of methods:

Drip Black Coffee
- Filter – Hot water is passed through finely-ground coffee within a filter
- Plunger/Cafetiere – Hot water is added to coarsely-ground coffee, and after steeping for 3-5 minutes a plunger with a fine mesh base is used to separate the grounds from the infusion
- Percolator – Coarsely-ground coffee in water is boiled and bubbled to the top of the percolator
- Espresso – A machine forces hot water through very finely-ground, compacted coffee into cups below. When properly prepared by a ‘barista’, the result is a golden brown liquid called the ‘crema’ on top of black coffee. One espresso ‘shot’ is between 1.5 fl oz/44 ml and 1.75 fl oz/52 ml, produced from 7 grams of ground coffee.
- Moka-Nepoletana – In a combination of espresso and percolator methods, water is boiled in the lower container of a double-chambered pot, and forced up through a tube then down through finely-ground coffee.
- Arab or Turkish – Finely-ground coffee with sugar in a cupful of water, is brought to the boil then taken off the heat up to 3 times, before being poured to drink as a strong-tasting coffee.
- K-Cup Caffeine- Keurig’s K-Cups are similar to the filter brewing style and have a similar taste and caffeine content.
Specialty and convenience coffee drinks include:
- Cappuccino: Espresso, some milk, and a thick head of milk foam, often sprinkled with cinnamon or cocoa powder
- Latte: Espresso with lots of milk
- Mocha: Latte with chocolate, often topped with whipped cream
- Americano: Espresso shot, plus hot water to fill the cup
- Macchiato: Espresso shot, plus a little frothed milk
- Cafe au lait: Brewed coffee, preferably dark French roast with chicory, with half scalded milk (not steamed), poured into the cuo together.
- Instant (or soluble) coffee: Dehydrated coffee powder or granules to which hot water (and/or hot or cold milk) is added
- Flavoured coffee drinks: Flavours introduced either to the beans after roasting, or after brewing by adding syrups (vanilla, caramel, peppermint etc) or alcohol (eg whiskey for Irish coffee)
- Coffee-infused liqueurs: Irish cream, rum cream etc
- Iced coffee: Brewed coffee, cooled then chilled, and stirred with crushed ice (possibly sweetened and with cold milk added)
Calories in Coffee Drinks
Unadulterated coffee (that is, only water added) has no calories. The calories in coffee drinks are present in the additives – lattes, mochas, iced espresso blended with sugar, whipped cream, ice cream, flavored syrups, alcohol, and so on.
| Coffee | Serving | Calories |
| Cafe au lait | 6 fluid oz/177 ml | 60 |
| Cappuccino, medium, skim milk | 14 fl oz/414 ml | 60 |
| Latte, medium, skim milk | 14 fl oz/414 ml | 110 |
| Espresso, double shot | 3 fl oz/89 ml | 0 |
| Iced coffee, sugar & whole milk | 8 fl oz/236 ml | 40 |
| Mocha coffee, medium, whole milk | 14 fl oz/414 ml | 290 |
| Instant with chicory | 6 fl oz/177 ml | 5 |
| Starbucks Pumpkin Spice Latte | 16 fl oz/177 ml (Grande) | 380 |
Moderate Caffeine Consumption Seems Best
Restrict intake to no more than 250mg of caffeine per day.
- Aim for moderate use of coffee – one serving of coffee ranges from about 80mg for a single shot (30ml) of arabica variety espresso to about 140 mg for strong drip coffee. (Starbucks drip can be even higher!) Caffeine content of coffee beans is between about 1 to 1.4% (Arabica coffee normally contains less caffeine than the Robusta variety). Generally, dark roast coffee has less caffeine than lighter roasts (the roasting process reduces the bean’s caffeine content).
- Use decaffeinated coffee, if it has been naturally decaffeinated or Swiss water processed (no chemicals have been introduced). Decaffeinated beans have only about 0.02% caffeine, so that one cup of decaf coffee has only around 2-4 mg of caffeine.
- Be aware of the caffeine content of other beverages (cola’s for example), snacks and candy (like chocolate).
- If you’re a tea drinker note that 8oz of regular tea can range between 47mg to 60mg, 8oz of green tea has 25mg, and the caffeine content of Matcha green tea is 70mg per 8oz serving.


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I drank alot of coffee and now i cant slip any more please help,this is depresing…;-(
Do a Caffeine Detox http://www.energyfiend.com/my-caffeine-detox
I just started high school, and I started drinking coffee with my meals at school. I was just wondering if the food would slow down the effects of the caffeine or not? If so, how much should I drink to keep me up through the day, because I start to dose around 1′o clock after having some for breakfast at six.
i love caffien is it true that u get shorter cuz if it iz then im scared
normally i drink it with out milk and sugar so what are the effect?
pls i want to find out that if coffee its affect your sexual activity been a young man?
Hi. I dont drink coffee that much, but when i do its only one cup (normally either a Latte or a Mocha) im in middle school, is it bad for me?
No. You are better off drinking this than an energy drink. Just be wary of adding any more sugar to the drink.
My dentist was having a difficult time numbing me up when she asked me if I had drank coffee that day. I admitted to 3 cups of coffee. She than said that coffee sometimes over stimulated the pain centers of the body. I had never heard of that before. What do you know about this.
I tek a lot of POWER HORSE,it contains some percentage of caffeine. Hop no harm?
Is there any side effect of cold(iced) coffee??
The same side effects as hot coffee
normali i dont like coffee but un fortunatly 2 years back i drink 4 cups off cappuccino within 1 hours in coffee shop .when i came back my room just i take shower, then i went for sleep on my bed after few minuts i get hypertentions and high b p lots off negative thoughts i cant sleep i am become fear ,after that i went hospital they given some medicin but still not finish my problem because off coffee still iam suffering with hyoertentions and fear ………..thats way iam not happy in my life i hate coffee
i think this is only your misconception and it is not due to coffee. i suggest you that u shud go to ur doctor and consults with him for ur complete checkup.
can coffee stop the growth of a person?
No. Coffee increases alertness and can cause insomnia. Excessive caffeine consumption in one’s youth can reduce the amount of sleep a person achieves, which can stunt growth. Indirectly, caffeine consumption can lead to stunted growth, but it is not a direct cause.
Um currently pregnant ,my mom has got serious issues with B.P ,so how bad is caffeine to us? Does t prevent iron absorbtion?
I did not like coffee until I tried it for health reasons. Do you know that it has diuretic effect?
Actually the latest research shows that it has a negative hydrating effect. This means the amount of water in the coffee is eliminated due to the diuretic effect of the caffeine.
Any advice on how to get off coffee except decaf?? My daily intake of coffee (120mg coffee per cup) ranges between 9-11 cups.
Cut back SLOW or u will have head ackes so bad u will not be able to stand it instead of 9-11 cups try 6 or 8 the one less and one less one week at a time till ur all off of it
http://www.diet-blog.com/08/how_to_quit_drinking_coffee.php
is it harmful to take in summer even as cold coffee ..?? does it cause acne and ,pimples..???
it has the exact same effect when cold as it does when hot. it’s still got the same caffeine in it. and no.
What, if any, are the psychological\emotional effects of caffeine on an drug addict whose recent use included crack cocaine. Could\does it cause depression??
coffee is simply good. Reasons best known 2 me. yea
I like the aroma of coffee that’s why I take it, but it makes me drink a lot of water and also feel weak. Are these feelings side effects? Should I stop taking coffee?
I take a lot of coca cola. At least one in a day or 2 days. I hope there is no problem with that.
well guys i don’t really like caffeine but i think it helps enough especially to student because it tries to keep them awake
I love coffee..but dont know why I always feeling dizzy if drink more than 2 cups..any Idea?
Hi Elle, check out this article: http://www.energyfiend.com/caffeine-allergy-top-20-symptoms that’s one of the symptoms of a caffeine allergy.
I see the normal suggested intake is around 250mg of caffiene daily.
*What if your daily intake of caffiene exceeds 2,000mg/or more of caffiene daily?
The way I make coffee; I probably consume 1,000mg in 5 cups or less & I drink around 2-3 pots of coffee a day. I actually get sick in the morning until I have my first cup.
I’d also like to know the effects the high caffiene has with the sidekick of Nicotine; if any effect at all physically.
Is takeing one cup a day good too the body
Most research would support the safety and even benefits of drinking one to two cups of coffee daily.
i read that coffee can affect eye vision.any thoughts?
I like it,only one cup is enough
@ Pat –
Pat — please talk with a doctor about your feet swelling. That can also be a symptom of serious heart problems — as it was for me, a few days before I had a heart attack.
I DRINK COKES- MY FEET SWELL UP-I KNOW IT’S BECAUSE I DRINK THEM- HOW CAN I GET OFF THEM SLOWLY?
just a cup per day is ok by me
I love coffee. I drink it all day long, even before I go to bed. I feel quite dependant on it though. I guess cutting down slowly so I don’t actually need it sounds like the right thing to do for
i drink like 5 pots a day maybe thats y i sleep like 3am